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Studies have confirmed that liver organoids express key enzymes, including members of the cytochrome P450 (CYP450) family and hepatic transporters, though often at lower levels compared to native liver tissue 14,15

This dual role makes it relevant to autoimmune conditions where microbial dysbiosis contributes to immune activation

This work was supported by the Norwegian Center for Stem Cell Research and National Core Facility for Human Pluripotent Stem Cells

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In some embodiments, the formulation or composition has a viscosity of less than about 10,000 cP

The systemic inflammation and immune dysregulation inherent to these conditions appear to impair the transport mechanisms that carry B12 from the bloodstream into the brain and spinal cord